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Mouse Lefty2 activation kit by CRISPRa

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SKU
GA216444
Lefty2 CRISPRa kit - CRISPR gene activation of mouse left-right determination factor 2
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Lefty2
Locus ID 320202
Components

GA216444G1, Lefty2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA216444G2, Lefty2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA216444G3, Lefty2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_177099
UniProt ID P57785
Synonyms 6030463A22Rik; Ebaf; Lefta; Leftb; lefty-2; lefty-B
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This protein is also important in self-renewal and differentiation of mouse embryonic stem cells. Mice lacking a functional copy of this gene exhibit defects in axial and left-right patterning. provided by RefSeq, Aug 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN509217 Lefty2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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