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Mouse Erlin2 activation kit by CRISPRa

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SKU
GA215194
Erlin2 CRISPRa kit - CRISPR gene activation of mouse ER lipid raft associated 2
  $1,657.00
4 Weeks*

Other products for "Erlin2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Erlin2
Locus ID 244373
Components

GA215194G1, Erlin2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA215194G2, Erlin2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA215194G3, Erlin2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_153592, NM_001364476, NM_001364477
UniProt ID Q8BFZ9
Synonyms BC036333; C87251; Spfh2
Summary Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN505349 Erlin2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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