Mouse Lrit3 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Lrit3 |
| Locus ID | 242235 |
| Components |
GA215033G1, Lrit3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215033G2, Lrit3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215033G3, Lrit3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001205102, NM_001287224 |
| UniProt ID | W8DXL4 |
| Synonyms | Gm421 |
| Summary | Required in retinal ON-bipolar cells for normal localization of the cation channel TRPM1 at dendrite tips (PubMed:25997951). May also have a role in cone synapse formation (PubMed:25997951). Might facilitate FGFR1 exit from the endoplasmic reticulum to the Golgi (By similarity). Could be a regulator of the FGFRs (By similarity).UniProtKB/Swiss-Prot Function |
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