Mouse Vtcn1 activation kit by CRISPRa

SKU
GA215029
Vtcn1 CRISPRa kit - CRISPR gene activation of mouse V-set domain containing T cell activation inhibitor 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Vtcn1
Locus ID 242122
Components

GA215029G1, Vtcn1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA215029G2, Vtcn1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA215029G3, Vtcn1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_178594
UniProt ID Q7TSP5
Synonyms B7h4; B7s1; B7x; BC032925
Summary Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN519289 Vtcn1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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