Mouse Ercc6l activation kit by CRISPRa

SKU
GA214696
Ercc6l CRISPRa kit - CRISPR gene activation of mouse excision repair cross-complementing rodent repair deficiency complementation group 6 like
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ercc6l
Locus ID 236930
Components

GA214696G1, Ercc6l gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214696G2, Ercc6l gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214696G3, Ercc6l gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_146235
UniProt ID Q8BHK9
Synonyms BC004701; D330021P09Rik
Summary DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. Functions as ATP-dependent DNA translocase. Can promote Holliday junction branch migration (in vitro).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN505327 Ercc6l - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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