Mouse Fgl1 activation kit by CRISPRa

SKU
GA214513
Fgl1 CRISPRa kit - CRISPR gene activation of mouse fibrinogen-like protein 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Fgl1
Locus ID 234199
Components

GA214513G1, Fgl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214513G2, Fgl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214513G3, Fgl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_145594
UniProt ID Q71KU9
Synonyms Mfire1
Summary Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 (PubMed:30580966). Responsible for LAG3 T-cell inhibitory function (PubMed:30580966). Binds LAG3 independently from MHC class II (MHC-II) (PubMed:30580966). In addition to its role in inhibiting inflammatory immune responses, also plays a role in hepatocytes (By similarity). Under normal physiological conditions, primarily secreted from hepatocytes and contributes to its mitogenic and metabolic functions (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN505953 Fgl1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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