Mouse Ano5 activation kit by CRISPRa

SKU
GA214444
Ano5 CRISPRa kit - CRISPR gene activation of mouse anoctamin 5
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ano5
Locus ID 233246
Components

GA214444G1, Ano5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214444G2, Ano5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214444G3, Ano5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001271879, NM_177694, NR_073508
UniProt ID Q75UR0
Synonyms 9330162L24; Gdd1; Tmem16e
Summary This gene encodes a member of the anoctamin family, which in mammals is comprised of 10 members. Anoctamin proteins are proposed to have eight transmembrane domains with both termini facing the cytoplasm and a C-terminal domain of unknown function. While some members have been characterized as calcium-activated chloride channels, this protein is reported to have little anion conductance activity. Elevated levels of this protein were found in dystrophic mice. In humans, mutations of this gene are associated with with musculoskeletal disorders such as myopathies, muscular dystrophy and gnathodiaphyseal dysplasia. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN501318 Ano5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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