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Mouse Kcnq5 activation kit by CRISPRa

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SKU
GA213899
Kcnq5 CRISPRa kit - CRISPR gene activation of mouse potassium voltage-gated channel, subfamily Q, member 5
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Kcnq5
Locus ID 226922
Components

GA213899G1, Kcnq5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213899G2, Kcnq5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213899G3, Kcnq5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001160139, NM_001310477, NM_023872
UniProt ID Q9JK45
Synonyms 7730402H11; 9230107O05Rik; AA589396; D1Mgi1
Summary Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. Therefore, it is important in the regulation of neuronal excitability. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN508690 Kcnq5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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