Mouse Tfb1m activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Tfb1m |
| Locus ID | 224481 |
| Components |
GA213695G1, Tfb1m gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213695G2, Tfb1m gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213695G3, Tfb1m gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_146074 |
| UniProt ID | Q8JZM0 |
| Synonyms | AI429207 |
| Summary | S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (By similarity).UniProtKB/Swiss-Prot Function |
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