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Mouse Ahsa1 activation kit by CRISPRa

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SKU
GA213501
Ahsa1 CRISPRa kit - CRISPR gene activation of mouse AHA1, activator of heat shock protein ATPase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ahsa1
Locus ID 217737
Components

GA213501G1, Ahsa1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213501G2, Ahsa1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213501G3, Ahsa1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_146036
UniProt ID Q8BK64
Synonyms BC023857; p38
Summary Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (By similarity). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN501014 Ahsa1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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