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Mouse Edem1 activation kit by CRISPRa

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SKU
GA212706
Edem1 CRISPRa kit - CRISPR gene activation of mouse ER degradation enhancer, mannosidase alpha-like 1
  $1,657.00
4 Weeks*

Other products for "Edem1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Edem1
Locus ID 192193
Components

GA212706G1, Edem1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212706G2, Edem1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212706G3, Edem1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_138677
UniProt ID Q925U4
Synonyms A130059K23Rik; EDEM; mKIAA0212
Summary Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN504997 Edem1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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