Mouse Asic3 activation kit by CRISPRa

SKU
GA212643
Asic3 CRISPRa kit - CRISPR gene activation of mouse acid-sensing (proton-gated) ion channel 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Asic3
Locus ID 171209
Components

GA212643G1, Asic3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212643G2, Asic3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212643G3, Asic3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001310474, NM_183000
UniProt ID Q6X1Y6
Synonyms Accn3; AW742291; DRASIC; SLNAC1; TNAC1
Summary Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN501680 Asic3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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