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Mouse Tlr3 activation kit by CRISPRa

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SKU
GA212551
Tlr3 CRISPRa kit - CRISPR gene activation of mouse toll-like receptor 3
  $1,657.00
4 Weeks*

Other products for "Tlr3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Tlr3
Locus ID 142980
Components

GA212551G1, Tlr3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212551G2, Tlr3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212551G3, Tlr3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_126166, NM_001357316, NM_001357317
UniProt ID Q99MB1
Synonyms AI957183
Summary Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN517626 Tlr3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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