Mouse Bsnd activation kit by CRISPRa

SKU GA212500

Bsnd CRISPRa kit - CRISPR gene activation of mouse barttin CLCNK type accessory beta subunit

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Bsnd
• Locus ID: 140475
• Components:

  GA212500G1, Bsnd gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA212500G2, Bsnd gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA212500G3, Bsnd gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_080458
• UniProt ID: Q8VIM4
• Synonyms: MGC47291
• Summary: Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.[UniProtKB/Swiss-Prot Function]