Mouse Rrn3 activation kit by CRISPRa

SKU GA211923

Rrn3 CRISPRa kit - CRISPR gene activation of mouse RRN3 RNA polymerase I transcription factor homolog (yeast)

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Rrn3
• Locus ID: 106298
• Components:

  GA211923G1, Rrn3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211923G2, Rrn3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211923G3, Rrn3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001039521
• UniProt ID: B2RS91
• Synonyms: AL023001; E130302O19Rik; R75565; TIF-1A; Tif1a
• Summary: Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction.[UniProtKB/Swiss-Prot Function]