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Mouse Vipas39 activation kit by CRISPRa

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SKU
GA211836
Vipas39 CRISPRa kit - CRISPR gene activation of mouse VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
  $1,657.00
4 Weeks*

Other products for "Vipas39"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Vipas39
Locus ID 104799
Components

GA211836G1, Vipas39 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211836G2, Vipas39 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211836G3, Vipas39 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001142580, NM_001142581, NM_134044
UniProt ID Q8BGQ1
Synonyms 6720456H09Rik; 9330175H22Rik; AI413782; hSPE-39; SPE-39; Spe39; Vipar
Summary Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be indepenedent of VPS33B (By similarity). May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indirect transcriptional regulation of E-cadherin.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN518894 Vipas39 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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