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Mouse Aldh6a1 activation kit by CRISPRa

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SKU
GA211834
Aldh6a1 CRISPRa kit - CRISPR gene activation of mouse aldehyde dehydrogenase family 6, subfamily A1
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Aldh6a1
Locus ID 104776
Components

GA211834G1, Aldh6a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211834G2, Aldh6a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211834G3, Aldh6a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_134042
UniProt ID Q9EQ20
Synonyms 1110038I05Rik; Mmsdh
Summary This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded enzyme is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This enzyme catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Mutations in the human gene result in Methylmalonate Semialdehyde Dehydrogenase Deficiency, characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Sep 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN501125 Aldh6a1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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