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Mouse Ezhip activation kit by CRISPRa

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SKU
GA211726
AU022751 CRISPRa kit - CRISPR gene activation of mouse expressed sequence AU022751
  $1,657.00
4 Weeks*

Other products for "Ezhip"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ezhip
Locus ID 102991
Components

GA211726G1, Ezhip gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211726G2, Ezhip gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211726G3, Ezhip gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001033211, NM_001166433
UniProt ID Q3UWZ4
Synonyms AU023811
Summary Inhibits PRC2/EED-EZH1 and PRC2/EED-EZH2 complex function by inhibiting EZH1/EZH2 methyltransferase activity, thereby causing down-regulation of histone H3 trimethylation at 'Lys-27' (H3K27me3) (PubMed:31086175). Probably inhibits methyltransferase activity by limiting the stimulatory effect of cofactors such as AEBP2 and JARID2 (By similarity). Inhibits H3K27me3 deposition during spermatogenesis and oogenesis (PubMed:31451685).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN501865 AU022751 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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