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Mouse Sh3bp4 activation kit by CRISPRa

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SKU
GA211506
Sh3bp4 CRISPRa kit - CRISPR gene activation of mouse SH3-domain binding protein 4
  $1,657.00
4 Weeks*

Other products for "Sh3bp4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Sh3bp4
Locus ID 98402
Components

GA211506G1, Sh3bp4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211506G2, Sh3bp4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211506G3, Sh3bp4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_133816
UniProt ID Q921I6
Synonyms AI594717; AW227605; BOG25
Summary May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN515714 Sh3bp4 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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