Mouse Ophn1 activation kit by CRISPRa

SKU
GA211422
Ophn1 CRISPRa kit - CRISPR gene activation of mouse oligophrenin 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ophn1
Locus ID 94190
Components

GA211422G1, Ophn1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211422G2, Ophn1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211422G3, Ophn1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001313754, NM_001313755, NM_001313756, NM_052976
UniProt ID Q99J31
Synonyms C130037N19Rik; Wtgr
Summary Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals (By similarity). Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN512607 Ophn1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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