Mouse Sytl2 activation kit by CRISPRa

SKU
GA211246
Sytl2 CRISPRa kit - CRISPR gene activation of mouse synaptotagmin-like 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Sytl2
Locus ID 83671
Components

GA211246G1, Sytl2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211246G2, Sytl2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211246G3, Sytl2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001040085, NM_001040086, NM_001040087, NM_001040088, NM_001289583, NM_001289584, NM_001289585, NM_001289586, NM_031394, NR_110348, NM_001368878
UniProt ID Q99N50
Synonyms AI266830; mKIAA1597; Slp2
Summary Isoform 11 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. Required for cytotoxic granule docking at the immunologic synapse. Isoform 1 may play a role in melanosome transport and vesicle trafficking. It controls melanosome distribution in the cell periphery and regulates melanocyte morphology. Isoform 1 acts as a positive mediator of mucus secretion by the surface mucus cells of the stomach. Mediates basal mucus secretion by gastric surface cells by promoting the proper granule biognesis and docking of mucus granules with the apical plasma membrane.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN517094 Sytl2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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