Mouse Abcc3 activation kit by CRISPRa

SKU GA210499

Abcc3 CRISPRa kit - CRISPR gene activation of mouse ATP-binding cassette, sub-family C (CFTR/MRP), member 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Abcc3
• Locus ID: 76408
• Components:

  GA210499G1, Abcc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA210499G2, Abcc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA210499G3, Abcc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_029600, NM_001363187, NM_001363189
• UniProt ID: B2RX12
• Synonyms: 1700019L09Rik; ABC31; MLP2; MOAT-D; MRP3
• Summary: May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes.[UniProtKB/Swiss-Prot Function]