Mouse Klhl24 activation kit by CRISPRa

SKU
GA210350
Klhl24 CRISPRa kit - CRISPR gene activation of mouse kelch-like 24
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Klhl24
Locus ID 75785
Components

GA210350G1, Klhl24 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA210350G2, Klhl24 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA210350G3, Klhl24 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_029436
UniProt ID Q8BRG6
Synonyms 1110046J11Rik; 4930429H24Rik; 6530402O20Rik; C85082
Summary Controls KRT14 levels during keratinocytes differentiation (PubMed:27798626). As part of the BCR(KLHL24) E3 ubiquitin ligase complex, mediates ubiquitination of KRT14 (By similarity). Specifically reduces kainate receptor-mediated currents in hippocampal neurons, most probably by modulating channel properties (By similarity).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN508863 Klhl24 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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