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Mouse Slx1b activation kit by CRISPRa

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SKU
GA210339
Slx1b CRISPRa kit - CRISPR gene activation of mouse SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
  $1,657.00
4 Weeks*

Other products for "Slx1b"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Slx1b
Locus ID 75764
Components

GA210339G1, Slx1b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA210339G2, Slx1b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA210339G3, Slx1b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_029420, NR_033446
UniProt ID Q8BX32
Synonyms 1110030E23Rik; 2410170E21Rik; 4833422P03Rik; AI853643; Giyd1; Giyd2
Summary Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN516265 Slx1b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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