Mouse Armcx3 activation kit by CRISPRa

SKU
GA208899
Armcx3 CRISPRa kit - CRISPR gene activation of mouse armadillo repeat containing, X-linked 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Armcx3
Locus ID 71703
Components

GA208899G1, Armcx3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA208899G2, Armcx3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA208899G3, Armcx3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_027870, NM_001358520, NM_001358521
UniProt ID Q8BHS6
Synonyms 1200004E24Rik; AI450003; ALEX3
Summary Regulates mitochondrial aggregation and transport in axons in living neurons (PubMed:22569362, PubMed:23844091). May link mitochondria to the Trak2-kinesin motor complex via its interaction with Miro and Trak2 (PubMed:22569362). Mitochondrial distribution and dynamics is regulated through Armcx3 protein degradation, which is promoted by PCK and negatively regulated by Wnt1 (PubMed:23844091). Enhances the Sox10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters (PubMed:19304657).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN501599 Armcx3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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