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Mouse Fendrr activation kit by CRISPRa

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SKU
GA207935
Fendrr CRISPRa kit - CRISPR gene activation of mouse Foxf1 adjacent non-coding developmental regulatory RNA
  $1,657.00
4 Weeks*

Other products for "Fendrr"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Fendrr
Locus ID 68790
Components

GA207935G1, Fendrr gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA207935G2, Fendrr gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA207935G3, Fendrr gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NR_045471, NR_130109
Summary This gene encodes a spliced long non-coding RNA transcribed from a bidirectional promoter shared with Foxf1 on the opposite strand. The encoded transcript is essential for normal development of the heart and body wall. It is thought to act by binding to polycomb repressive complex 2 (PRC2) and/or TrxG/MLL complexes to promote the methylation of the promoters of target genes, thus reducing their expression. It plays a role in cell fate determination in tissues derived from the lateral plate mesoderm. Knockout models reveal loss of this gene is lethal in mice. Alternatively spliced transcript variants have been identified. provided by RefSeq, Dec 2014
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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