Mouse Spc24 activation kit by CRISPRa

SKU
GA207427
Spc24 CRISPRa kit - CRISPR gene activation of mouse SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Spc24
Locus ID 67629
Components

GA207427G1, Spc24 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA207427G2, Spc24 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA207427G3, Spc24 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_026282, NM_001357331, NR_151672, NR_151673
UniProt ID Q9D083
Synonyms 2410030K01Rik; AV109292; Spbc24
Summary Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN516571 Spc24 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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