Mouse Tespa1 activation kit by CRISPRa

SKU
GA207412
Tespa1 CRISPRa kit - CRISPR gene activation of mouse thymocyte expressed, positive selection associated 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Tespa1
Locus ID 67596
Components

GA207412G1, Tespa1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA207412G2, Tespa1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA207412G3, Tespa1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_183264
UniProt ID Q3U132
Synonyms 5830405N20Rik; A430001F24Rik; AI450549
Summary May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment (By similarity). Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN517421 Tespa1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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