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Mouse Ndc80 activation kit by CRISPRa

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SKU
GA207110
Ndc80 CRISPRa kit - CRISPR gene activation of mouse NDC80 kinetochore complex component
  $1,657.00
4 Weeks*

Other products for "Ndc80"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ndc80
Locus ID 67052
Components

GA207110G1, Ndc80 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA207110G2, Ndc80 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA207110G3, Ndc80 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_023294
UniProt ID Q9D0F1
Synonyms 2610020P18Rik; AV139730; HEC; HEC1; Kntc2
Summary Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN510802 Ndc80 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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