Mouse Ccnh activation kit by CRISPRa

SKU
GA206898
Ccnh CRISPRa kit - CRISPR gene activation of mouse cyclin H
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ccnh
Locus ID 66671
Components

GA206898G1, Ccnh gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206898G2, Ccnh gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206898G3, Ccnh gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001347587, NM_001347588, NM_023243
UniProt ID Q61458
Synonyms 6330408H09Rik; AI661354; AV102684; AW538719
Summary Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN502818 Ccnh - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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