Mouse Smpd3 activation kit by CRISPRa

SKU
GA206320
Smpd3 CRISPRa kit - CRISPR gene activation of mouse sphingomyelin phosphodiesterase 3, neutral
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Smpd3
Locus ID 58994
Components

GA206320G1, Smpd3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206320G2, Smpd3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206320G3, Smpd3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_021491
UniProt ID Q9JJY3
Synonyms 4631433G07Rik; AI427456; AW537966; fro; nSMase2
Summary Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Acts as a regulator of postnatal development and participates in bone and dentin mineralization. Overexpression enhances cell death, suggesting that it may be involved in apoptosis control.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN516346 Smpd3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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