Mouse Naa80 activation kit by CRISPRa

SKU GA205972

Naa80 CRISPRa kit - CRISPR gene activation of mouse N(alpha)-acetyltransferase 80, NatH catalytic subunit

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Naa80
• Locus ID: 56441
• Components:

  GA205972G1, Naa80 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205972G2, Naa80 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205972G3, Naa80 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_019750
• UniProt ID: Q9R123
• Synonyms: AI225910; Fus2
• Summary: N-alpha-acetyltransferase that specifically mediates the acetylation of the acidic amino terminus of processed forms of beta- and gamma-actin (ACTB and ACTG, respectively). N-terminal acetylation of processed beta- and gamma-actin regulates actin filament depolymerization and elongation. In vivo, preferentially displays N-terminal acetyltransferase activity towards acid N-terminal sequences starting with Asp-Asp-Asp and Glu-Glu-Glu. In vitro, shows high activity towards Met-Asp-Glu-Leu and Met-Asp-Asp-Asp. May act as a tumor suppressor.[UniProtKB/Swiss-Prot Function]