Mouse Socs6 activation kit by CRISPRa

SKU
GA205732
Socs6 CRISPRa kit - CRISPR gene activation of mouse suppressor of cytokine signaling 6
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Socs6
Locus ID 54607
Components

GA205732G1, Socs6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205732G2, Socs6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205732G3, Socs6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_018821
UniProt ID Q9JLY0
Synonyms 1500012M23Rik; 5830401B18Rik; AI447482; Cis4; Cish4; HSPC060; SOCS-4; SOCS-6; Socs4; SSI4; STAI4
Summary SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN516459 Socs6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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