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Mouse Rassf5 activation kit by CRISPRa

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SKU
GA205678
Rassf5 CRISPRa kit - CRISPR gene activation of mouse Ras association (RalGDS/AF-6) domain family member 5
  $1,657.00
4 Weeks*

Other products for "Rassf5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Rassf5
Locus ID 54354
Components

GA205678G1, Rassf5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205678G2, Rassf5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205678G3, Rassf5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001311094, NM_001313731, NM_018750
UniProt ID Q5EBH1
Synonyms 1300019G20Rik; Maxp1; Nore1; Nore1A; Nore1B; Rapl
Summary Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing (By similarity). May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN514519 Rassf5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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