Mouse Lsm4 activation kit by CRISPRa

SKU GA205363

Lsm4 CRISPRa kit - CRISPR gene activation of mouse LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Lsm4
• Locus ID: 50783
• Components:

  GA205363G1, Lsm4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205363G2, Lsm4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205363G3, Lsm4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015816, NM_001359042
• UniProt ID: Q9QXA5
• Summary: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.[UniProtKB/Swiss-Prot Function]