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Mouse Cngb3 activation kit by CRISPRa

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SKU
GA205303
Cngb3 CRISPRa kit - CRISPR gene activation of mouse cyclic nucleotide gated channel beta 3
  $1,657.00
4 Weeks*

Other products for "Cngb3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Cngb3
Locus ID 30952
Components

GA205303G1, Cngb3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205303G2, Cngb3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205303G3, Cngb3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_013927
Synonyms CCNC2; CNG6; Cngbeta2
Summary Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones (By similarity). Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3.UniProtKB/Swiss-Prot Function
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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