Mouse Glrx3 activation kit by CRISPRa

SKU
GA205282
Glrx3 CRISPRa kit - CRISPR gene activation of mouse glutaredoxin 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Glrx3
Locus ID 30926
Components

GA205282G1, Glrx3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205282G2, Glrx3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205282G3, Glrx3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_023140, NM_001348093
UniProt ID Q9CQM9
Synonyms PICOT; Txnl2
Summary Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates 2Fe-2S cluster insertion into a subset of cytosolic proteins (By similarity). Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (PubMed:16809552, PubMed:18258855, PubMed:18929570). Required for hemoglobin maturation. Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN506538 Glrx3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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