Mouse Aadat activation kit by CRISPRa

SKU GA204815

Aadat CRISPRa kit - CRISPR gene activation of mouse aminoadipate aminotransferase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Aadat
• Locus ID: 23923
• Components:

  GA204815G1, Aadat gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA204815G2, Aadat gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA204815G3, Aadat gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_011834
• UniProt ID: Q9WVM8
• Synonyms: Aadt; AI875679; Kat2; KATII; Kyat2; mKat-2
• Summary: Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) (By similarity).[UniProtKB/Swiss-Prot Function]