Mouse Uchl1 activation kit by CRISPRa

SKU GA204526

Uchl1 CRISPRa kit - CRISPR gene activation of mouse ubiquitin carboxy-terminal hydrolase L1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Uchl1
• Locus ID: 22223
• Components:

  GA204526G1, Uchl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA204526G2, Uchl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA204526G3, Uchl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_011670
• UniProt ID: Q9R0P9
• Synonyms: AW822034; C88048; gad; PGP 9.5; PGP9.5; R75593; UCH-L1; UCHL-1
• Summary: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins (Probable). This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin (PubMed:12913066). Also binds to free monoubiquitin and may prevent its degradation in lysosomes (PubMed:12913066). The homodimer may have ATP-independent ubiquitin ligase activity (By similarity).[UniProtKB/Swiss-Prot Function]