Mouse Atxn1 activation kit by CRISPRa

SKU
GA203770
Atxn1 CRISPRa kit - CRISPR gene activation of mouse ataxin 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Atxn1
Locus ID 20238
Components

GA203770G1, Atxn1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203770G2, Atxn1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203770G3, Atxn1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001199304, NM_001199305, NM_009124
UniProt ID P54254
Synonyms 2900016G23Rik; Atx1; C85907; ENSMUSG00000074917; Gm10786; Sca1
Summary Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (By similarity). May be involved in RNA metabolism (By similarity). In concert with CIC and ATXN1L, involved in brain development (PubMed:28288114).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN501849 Atxn1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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