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Mouse Rab12 activation kit by CRISPRa

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SKU
GA203524
Rab12 CRISPRa kit - CRISPR gene activation of mouse RAB12, member RAS oncogene family
  $1,657.00
4 Weeks*

Other products for "Rab12"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Rab12
Locus ID 19328
Components

GA203524G1, Rab12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203524G2, Rab12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203524G3, Rab12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_024448
UniProt ID P35283
Synonyms 2900054P15Rik; AW555448; C77700
Summary The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN514331 Rab12 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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