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Mouse Nectin2 activation kit by CRISPRa

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SKU
GA203510
Nectin2 CRISPRa kit - CRISPR gene activation of mouse nectin cell adhesion molecule 2
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Nectin2
Locus ID 19294
Components

GA203510G1, Nectin2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203510G2, Nectin2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203510G3, Nectin2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001159724, NM_008990
UniProt ID P32507
Synonyms AI325026; AI987993; Cd112; MPH; nectin-2; Pvr; Pvrl2; Pvs
Summary Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN514268 Nectin2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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