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Mouse Pnoc activation kit by CRISPRa

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SKU
GA202949
Pnoc CRISPRa kit - CRISPR gene activation of mouse prepronociceptin
  $1,657.00
4 Weeks*

Other products for "Pnoc"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Pnoc
Locus ID 18155
Components

GA202949G1, Pnoc gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202949G2, Pnoc gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202949G3, Pnoc gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001205075, NM_010932
UniProt ID Q64387
Synonyms N/OFQ; Npnc1; OFQ/N
Summary This gene encodes the precursor for neuropeptides that have been implicated in a wide range of physiological roles such as transmission and sensitivity to pain, learning, memory, anxiety and depression, in the central nervous system. The encoded protein is a precursor that is proteolytically processed to generate multiple biologically active peptides including nociceptin and nocistatin which have opposite functions in pain transmission. Mice lacking the encoded protein display increased anxiety, elevated basal pain threshold and impaired adaptation to repeated stress. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN513543 Pnoc - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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