Mouse Meg3 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Meg3 |
| Locus ID | 17263 |
| Components |
GA202632G1, Meg3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202632G2, Meg3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202632G3, Meg3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_144513, NR_003633, NR_027651, NR_027652, NR_046475, NR_104450, NR_104451 |
| Summary | This gene is paternally-imprinted and thus expressed predominantly from the maternal allele. It generates alternatively-spliced long non protein-coding RNAs that overlap with the microRNAs Mir770 and Mir1906-1. Transcripts from this gene function as negative regulators of growth and may be down-regulated in tumor cells. This gene is expressed in a reciprocal pattern from the nearby Dlk1 (delta-like 1 homolog) gene, which is paternally-expressed. Deletion of this locus disrupts imprinting in this genomic region and results in perinatal morbidity. provided by RefSeq, Dec 2013 |
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