Mouse Kcnj6 activation kit by CRISPRa

SKU
GA202272
Kcnj6 CRISPRa kit - CRISPR gene activation of mouse potassium inwardly-rectifying channel, subfamily J, member 6
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Kcnj6
Locus ID 16522
Components

GA202272G1, Kcnj6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202272G2, Kcnj6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202272G3, Kcnj6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001025584, NM_001025585, NM_001025590, NM_010606
UniProt ID P48542
Synonyms BIR1; GIRK2; KATP2; KCNJ7; Kir3.2; weaver; wv
Summary This potassium channel is controlled by G proteins. It plays a role in granule cell differentiation, possibly via membrane hyperpolarization. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN508660 Kcnj6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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