Mouse Itpa activation kit by CRISPRa

SKU
GA202222
Itpa CRISPRa kit - CRISPR gene activation of mouse inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Itpa
Locus ID 16434
Components

GA202222G1, Itpa gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202222G2, Itpa gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202222G3, Itpa gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_025922, NM_001362648
UniProt ID Q9D892
Synonyms 2010016I08Rik; AU020102; Itp
Summary Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN508512 Itpa - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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