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Mouse Il10 activation kit by CRISPRa

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SKU
GA202112
Il10 CRISPRa kit - CRISPR gene activation of mouse interleukin 10
  $1,657.00
4 Weeks*

Other products for "Il10"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Il10
Locus ID 16153
Components

GA202112G1, Il10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202112G2, Il10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202112G3, Il10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_010548
UniProt ID P18893
Synonyms CSIF; Il-10
Summary This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. provided by RefSeq, Sep 2015
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Documents
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Other Versions
SKU Description Size Price
KN508218 Il10 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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