Mouse Fkbp1a activation kit by CRISPRa

SKU
GA201426
Fkbp1a CRISPRa kit - CRISPR gene activation of mouse FK506 binding protein 1a
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Fkbp1a
Locus ID 14225
Components

GA201426G1, Fkbp1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201426G2, Fkbp1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201426G3, Fkbp1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001302077, NM_001302078, NM_001302079, NM_001302080, NM_008019, NR_126058
UniProt ID P26883
Synonyms Fkbp; Fkbp1; FKBP12
Summary This gene is a member of the immunophilin family. The encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, and is associated with immunoregulation, protein folding, receptor signaling, protein trafficking and T-cell activation. It may modulate the calcium release activity of the ryanodine receptor Ryr1. It also interacts with the type I TGF-beta receptor. Disruption of this gene in mouse causes severe ventricular defects. Pseudogenes of this gene have been defined on chromosomes 4, 10, 14, and 16. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN505988 Fkbp1a - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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