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Mouse Fbn1 activation kit by CRISPRa

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SKU
GA201366
Fbn1 CRISPRa kit - CRISPR gene activation of mouse fibrillin 1
  $1,657.00
4 Weeks*

Other products for "Fbn1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Fbn1
Locus ID 14118
Components

GA201366G1, Fbn1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201366G2, Fbn1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201366G3, Fbn1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_007993
UniProt ID Q61554
Synonyms AI536462; B430209H23; Fib-1; Tsk
Summary This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Homozygous knockout mice for this gene exhibit impaired aortic development and early postnatal death, which was attributed to a deficiency in the fibrillin-1 protein. Mice with a hypomorphic allele of this gene exhibit impaired glucose homeostasis, likely due to a reduction in serum asprosin levels. provided by RefSeq, Apr 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN505779 Fbn1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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