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Mouse Fas activation kit by CRISPRa

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SKU
GA201356
Fas CRISPRa kit - CRISPR gene activation of mouse Fas (TNF receptor superfamily member 6)
  $1,657.00
4 Weeks*

Other products for "Fas"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Fas
Locus ID 14102
Components

GA201356G1, Fas gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201356G2, Fas gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201356G3, Fas gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001146708, NM_007987
UniProt ID P25446
Synonyms AI196731; APO1; APT1; CD95; lpr; TNFR6; Tnfrsf6
Summary Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN505761 Fas - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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